Dr. Pascal Mock
Pascal MOCK, MD, MSc, studied medicine at the Faculty of Medicine of the University of Geneva (Switzerland).
After practicing the profession of obstetrician and gynecologist at the University Hospital of Geneva (HUG), he continued his specialization in reproductive medicine in Paris (France) at the Antoine-Béclère hospital leading to a Master in reproductive physiology at the Pierre and Marie Curie University (Paris VI, 1998). Upon returning to Switzerland in 2001, he obtained the FMH certification in reproductive medicine.
Dr. Mock's area of research is embryo implantation. Between 1999 and 2001 he was director of a Swiss national fund for scientific research, working on the biological activity of a new placental molecule from the insulin family (INSL4). He is the author of several high-level scientific publications on infertility and embryo implantation. He also lectured at the University of Geneva
In 2004 with Martin Velasco, he founded ANECOVA, a Swiss biotechnology company, in order to develop his invention, a new culture system in vivo in medically assisted procreation (ART). His collaboration with EPFL was important during this creative period.
In 2009, he assisted the first baby in the world born from in vivo fertilization made possible using this new system at the Grangettes clinic in Geneva.
Relaxin 2000Authors:Geoffrey W. Tregear, Richard Ivell, Ross A. Bathgate, John D. WadeEditor: Springer Science & Business Media, 29 juin 2013
An in vivo culture system for human embryos using an encapsulation technology: a pilot studyAuthors:C. Blockeel, P. Mock, G. Verheyen, N. Bouche, Ph. Le Goff, Y. Heyman, C. Wrenzycki, K. Höffmann, H. Niemann, P. Haentjens, M.J. de Los Santos, M. Fernandez-Sanchez, M. Velasco, P. Aebischer, P. Devroey, and C. Simon (2009)Editor: Reprod 2009;24:790–796.
Effects of human chorionic gonadotrophin on trophoblastAuthors:Islami D, Mock P and Bischof P (2001)Editor: Seminars in Reproductive Medecine 19, 49-53
Simultaneous bilateral tubal pregnancy after intracytoplasmic sperm injection treated by conservative medical treatment : Interest of sonographic follow-up.Authors:Mock P, Olivennes F, Doumerc S, Frydman R and Fernandez H.(2001)Editor: Eur. J Obstet. Gynecol. Reprod. Biol., 94, 155-157.
Expression of pro-EPIL peptides, encoded by the insulin-like4 (INSL4) gene, in chromosomally abnormal pregnanciesAuthors:Mock P, Frydman R, Bellet D, Chassin D, Bischof P, Campana A, Bidart JM. (2000)Editor: J. Cl. Endocrinol. Metab., 85, 3941-3944.
Choriocarcinoma-like hCG and human chorionic gonadotropin bioactivity during the first trimester of pregnancy.Authors:Mock P, Kovalevskaya G, O’Connor D, Campana A. (2000)Editor: Hum. Reprod., 15, 2209-2214.
Pro-EPIL forms are present in amniotic fluid and maternal serum during normal pregnancy.Authors:Mock P, Frydman R, Bellet D, Diawara DA, Lavaissiere L, Troalen F, Bidart JM. (1999)Editor: J. Cl. Endocrinol. Metab., 84, 2253-2254.
Are women requiring unplanned intrapartum epidural analgesia different in a low-obstetrical risk population?Authors:Mock P, Santos-Eggimann B, Bérod ACl, Ditesheim PJ, Paccaud F. (1999)Editor: International J. Obst. Anaest., 8, 94-100.
Modulation of human chorionic gonodotrophin bioactivity during the first trimester of pregnancy.Authors:Mock P, Bischof P, Rivest R, Campana A, Chardonnens D. (1998)Editor: Hum. Reprod., 13, 2629-2632.
The apparent late half-life of human chorionic gonadotropin (hCG) after surgical treatment for ectopic pregnancy. A new approach to diagnose persistent trophoblastic activity.Authors:Mock P, Chardonnens D, Stamm P, Bischof P, Campana A. (1998)Editor: Eur. J Obstet. Gynecol. Reprod. Biol., 78, 99-102.
Identification of pro-EPIL and EPIL peptides translated from Insulin-like 4 (INSL4) mRNA in human placenta.Authors:Bellet D, Lavaissière L, Mock P, Laurent A, Sabourin JC, Bedossa P, Le bouteiller P, Frydman R, Troalen F, Bidart JM (1997)Editor: J. Clin. Endocrinol. Metab., 82, 3169-3172.
Thesis and dissertations
Difficult IVF embryo transfer : Are ovarian steroids implicated ? A Hypothesis (submission to Fertility and Sterility on November 2001)
El-Minawi AM, Campana A, Mock P.
Secretion of human chorionic gonadotrophin (hCG) and gelatinase A (MMP-2) by trophoblastic cells : Up- and down-regulation by relaxin (RLX). Manuscript published in the Proceedings of RELAXIN 2000-3rd International Conference on Relaxin and Related Peptides in March 2001
Mock P, Meisser A, Wuillemin C, Araman M, Campana A, Bischof P. (2000)
Etude de l’expression de early placenta insulin-like (EPIL), produit du gène INSL4, au niveau du placenta et de l’utérus. Mémoire de Diplôme d’Etudes Approfondies de Physiologie de la Reproduction, Responsable scientifique : Professeur Jean-Michel Bidart, Université Paris VI, Pierre et Marie Curie, Paris
Mock P. (1998)
Are women requiring unplanned intrapartum epidural analgesia different in a low-obstetrical risk population?
Thèse de Doctorat en Médecine, Université de Lausanne, Directeur de Thèse : Professeur Fred Paccaud
Mock, P. (1998)
Difficult IVF embryo transfer : Are ovarian steroids implicated ?Authors:El-Minawi AM, Campana A, Mock P.Editor: A Hypothesis Presentation at the 12th World Congress on in vitro fertilization and molecular reproduction in March 16-19 2001, Buenos Aires, Argentina
Localization of tyrosine phosphorylated proteins in human sperm and relation to IVF success.Authors:Urner F, Lucas H, Sakkas D, Chardonnens D, Bianchi G, Mock P, Campana A, Leppens-Luisier G.Editor: Presentation at ESHRE 2001, Lausanne, Switzerland.
Secretion of human chorionic gonadotrophin (hCG) and gelatinase A (MMP-2) by trophoblastic cells : Up-regulation by relaxin (RLX)Authors:Mock P, Meisser A, Vuillemin C, Araman M, Campana A, Bischof P.Editor: Presentation at the BAS/BFS/SSF Joint Fertility Societies Meeting, EICC, 31st July-2nd August, 2000, Edinburgh, UK
Mock intrauterine inseminations (IUI) to study end follicular phase uterine contractility.Authors:De Ziegler D, Brioschi PA, Howarth N, Mock P, Fanchin R, Bulletti C.Editor: Presentation at the American Society for Reproductive Medicine, 56th Annual Meeting-October 21-25, 2000, San Diego, CA. Published in Fertility and Sterility
G1.2/G2.2 : Effect on mouse embryo development and preliminary results in human IVF.Authors:Leppens-Luisier, G., Lucas, H., Chardonnens, D., de Ziegler, D., Bianchi, P.G., Mock, P., Campana, A., Urner, F.Editor: Presentation at the American Society for Reproductive Medicine, 56th Annual Meeting-October 21-25, 2000, San Diego, CA
Homolateral uterine artery impedance is preferentially lowered by the corpus luteum suggesting direct effects of this organ on uterine blood flow through a local circulatory phenomenon.Authors:Mock, P., Luedicke, F., Chardonnens, D., Bianchi, G., Bischof, P., De Ziegler, D. And Campana, A.Editor: Oral presentation at the 11th World Congress on In Vitro Fertilization and Human Reproductive Genetics in Sydney on May 1999
Breast cancer and risk factors : A comparative epidemiological study between a low and a high risk population.Authors:Straccia, A.-T., Vlastos, G., Mock, P., Huang, J., Li, H.W., Campana, A., Morabia, A.Editor: Poster session at the First European Breast Cancer Conference, Florence, 29th September-3rd October 1998
Balance sheet n ° 13 30 June 2010 Extract pages 86-87
University of Geneva
Anecova press release Le Temps 15 dec 2009
World Economic Forum Davos
With Martin VELASCO
Patent application EP 1639972 A1
Swiss Society of Medicine FMH
University of Lausanne
Pierre and Marie Curie University, Paris VI
Annual Conference, Fertility Societies', University of York, 16-18 Jul 1997
University of Geneva
US2004261799 (A1) - Intrauterine device, method of making such a device and method for putting active elements within the uterine cavity
Member of Learned Societies
American Society for Reproductive Medecine
Alpha Scientiste in Reproductive Medecine
British Fertility Society
European Society of Human Reproduction and Embroylogy
Société Suisse de Gynécologie et Obstétrique (SSGO)
FNRS (N° 32-59471.99 : 210 000 Frs)
Requérant principal : P. Mock.
Corequérants : Prof. A. Campana, Prof P. Bischof
Early placenta insulin-like (EPIL): research of in vitro biological activities in reproduction.